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Classics in ECT: Abrams LTE on Suicide Prevention With ECT, Am J Psych 1969

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 "Classics in ECT" brings you this LTE from Richard Abrams, from 1969: Suicide  and ECT. Abrams R. Am J Psychiatry. 1969 Aug;126(2):272. doi: 10.1176/ajp.126.2.272. PMID:  5804820                                       The letter is here: To the point, this brief LTE from ECT scholar Richard Abrams is particularly relevant today, as we finally have excellent data to support the role of ECT in suicide prevention: Electroconvulsive Therapy and the Risk of  Suicide   in Hospitalized Patients With Major Depressive Disorder. Rönnqvist I, Nilsson FK, Nordenskjöld A. JAMA Netw Open. 2021 Jul 1;4(7):e2116589. doi: 10.1001/jamanetworkopen.2021.16589. PMID:  34287633 Risk of  suicide   death following electroconvulsive therapy treatment for depression: a propensity score-weighted, retrospective cohort study in Canada. Kaster TS , Blumberger DM, Gomes T, Sutradhar R, Wijeysundera DN, Vigod SN. Lancet Psychiatry. 2022 Jun;9(6):435-446. doi: 10.1016/S2215-0366(22)00077-3. Epub 2022 Apr 26.

Systematic Review of Treatments For Agitation in TBI: ECT Mentioned

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Out on PubMed, from researchers in Australia, is this review: Effectiveness of Non-Pharmacological Interventions for Agitation during Post-Traumatic Amnesia following Traumatic Brain Injury: A Systematic Review. Carrier SL, Ponsford J, Phyland RK, Hicks AJ, McKay A. Neuropsychol Rev. 2022 Jun 10. doi: 10.1007/s11065-022-09544-5. Online ahead of print.  PMID:  35687261   Review. The abstract is copied below: Agitation is common in the early recovery period following traumatic brain injury (TBI), known as post-traumatic amnesia (PTA). Non-pharmacological interventions are frequently used to manage agitation, yet their efficacy is largely unknown. This systematic review aims to synthesize current evidence on the effectiveness of non-pharmacological interventions for agitation during PTA in adults with TBI. Key databases searched included MEDLINE Ovid SP interface, PubMed, CINAHL, Excerpta Medica Database, PsycINFO and CENTRAL, with additional online reviewing of key journals and clinical

Functional Connectivity Changes With ECT: New EEG Study From China

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 Out on PubMed, from investigators in China, is this study: Electroconvulsive  Therapy-Induced Changes in Functional Brain Network of Major Depressive Disorder Patients: A Longitudinal Resting-State Electroencephalography Study. Sun S, Yang P, Chen H, Shao X, Ji S, Li X, Li G, Hu B. Front Hum Neurosci. 2022 May 18;16:852657. doi: 10.3389/fnhum.2022.852657. eCollection 2022.  PMID:  35664348   The abstract is copied below: Objectives:  Several studies have shown abnormal network topology in patients with major depressive disorder (MDD). However, changes in functional brain networks associated with electroconvulsive therapy (ECT) remission based on electroencephalography (EEG) signals have yet to be investigated. Methods:  Nineteen-channel resting-state eyes-closed EEG signals were collected from 24 MDD patients pre- and post-ECT treatment . Functional brain networks were constructed by using various coupling methods and binarization techniques. Changes in functional connectivity and net

ALFF Changes and ECT: New Study From China

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 Out on PubMed, from researchers in China, is this study: Changes in the amplitude of low-frequency fluctuations in specific frequency bands in major depressive disorder after  electroconvulsive  therapy. Li XK, Qiu HT, Hu J, Luo QH. World J Psychiatry. 2022 May 19;12(5):708-721. doi: 10.5498/wjp.v12.i5.708. eCollection 2022 May 19. PMID:  35663299   The abstract is copied below: Background: Major depressive disorder (MDD) tends to have a high incidence and high suicide risk. Electroconvulsive therapy (ECT) is currently a relatively effective treatment for MDD. However, the mechanism of efficacy of ECT is still unclear. Aim: To investigate the changes in the amplitude of low-frequency fluctuations in specific frequency bands in patients with MDD after ECT. Methods: Twenty-two MDD patients and fifteen healthy controls (HCs) were recruited to this study. MDD patients received 8 ECT sessions with bitemporal placement. Resting-state functional magnetic resonance imaging was adopted to exam

Risperidone, ECT and the QTc Interval: Study From Iran

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 Out on PubMed, from investigators in Iran, is this paper: The effect of risperidone and electroconvulsive therapy on corrected QT interval in electrocardiogram of psychiatric patients. Rezaei B, Javdani H, Soleimannejad M, Dodangeh S. ARYA Atheroscler. 2021 Jul;17(4):1-6. doi: 10.22122/arya.v17i0.2235. PMID:  35685233   The abstract is copied below: Background: Some types of antidepressants and antipsychotic medications have cardiovascular side effects that can be life-threatening. Electroconvulsive therapy (ECT) is capable of generating physiological stress and may lead to increased QT interval followed by arrhythmias. Risperidone can also increase the risk of arrhythmia by increasing the corrected QT (QTc) interval. Since many patients require co-administration of risperidone and ECT, this study aimed to investigate the concurrent effect of ECT and risperidone administration on the QTc interval. Methods: For this cross-sectional study, 60 patients (18-65 years) admitted in 22 Bahman

Trial of "Hybrid ECT" From China

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Out on PubMed, from investigators in China, is this study: Improved Safety of Hybrid Electroconvulsive Therapy Compared With Standard Electroconvulsive Therapy in Patients With Major Depressive Disorder: A Randomized, Double-Blind, Parallel-Group Pilot Trial. Zhang JY, Xu SX, Zeng L, Chen LC, Li J, Jiang ZY, Tan BJ, Gu CL, Lai WT, Kong XM, Wang J, Rong H, Xie XH. Front Psychiatry. 2022 May 23;13:896018. doi: 10.3389/fpsyt.2022.896018. eCollection 2022.  PMID:   35677877 The abstract is copied below: Objectives: ECT is a rapid and effective treatment for depression. While efficacy is often remarkable over the initial 3-4 sessions, the efficacy of later sessions is less rapid, and the side-effects, especially cognitive impairment limit its use. To preliminarily compare the efficacy and acceptability of a novel hybrid-ECT (HECT) protocol for patients with major depressive disorder (MDD) with standard ECT, we conducted this pilot trial. Methods: Thirty patients were randomly assigned to E

Classics in ECT: Medcraft Glissando Unit in JAMA, 1954

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 "Classics in ECT" brings you this announcement from JAMA in 1954: MEDCRAFT  glissando  type shock therapy unit, model B-24. [No authors listed] J Am Med Assoc. 1954 May 8;155(2):126. PMID:  13151902 Here is an announcement in JAMA in 1954 from the Council on Physical Medicine and Rehabilitation "Apparatus Accepted" section. This early Medcraft had the "glissando" feature, for gradual application of the stimulus. It looks pretty modern, compared to the "Tractolater" (see above).