Risperidone, ECT and the QTc Interval: Study From Iran
Out on PubMed, from investigators in Iran, is this paper: The effect of risperidone and electroconvulsive therapy on corrected QT interval in electrocardiogram of psychiatric patients. Rezaei B, Javdani H, Soleimannejad M, Dodangeh S. ARYA Atheroscler. 2021 Jul;17(4):1-6. doi: 10.22122/arya.v17i0.2235. PMID: 35685233 The abstract is copied below: Background: Some types of antidepressants and antipsychotic medications have cardiovascular side effects that can be life-threatening. Electroconvulsive therapy (ECT) is capable of generating physiological stress and may lead to increased QT interval followed by arrhythmias. Risperidone can also increase the risk of arrhythmia by increasing the corrected QT (QTc) interval. Since many patients require co-administration of risperidone and ECT, this study aimed to investigate the concurrent effect of ECT and risperidone administration on the QTc interval. Methods: For this cross-sectional study, 60 patients (18-65 years) admitted in 22 Bahman