Central-positive Complexes in ECT-induced Seizures: EEG Study From Wash U. St. Louis
Out on PubMed, from investigators at Washington University in St. Louis, is this study: Central-positive complexes in ECT -induced seizures: Possible evidence for thalamocortical mechanisms. Huels ER, Kafashan M, Hickman LB, Ching S, Lin N, Lenze EJ, Farber NB, Avidan MS, Hogan RE, Palanca BJA. Clin Neurophysiol. 2022 Dec 9;146:77-86. doi: 10.1016/j.clinph.2022.11.015. Online ahead of print. PMID: 36549264 The abstract is copied below: Objective: Central-positive complexes (CPCs) are elicited during electroconvulsive therapy (ECT) as generalized high-amplitude waveforms with maximum positive voltage over the vertex. While these complexes have been qualitatively assessed in previous literature, quantitative analyses are lacking. This study aims to characterize CPCs across temporal, spatial, and spectral domains. Methods: High-density 64-electrode electroencephalogram (EEG) recordings during 50 seizures acquired from 11 patients undergoing right unilateral ECT allowed for evaluation of