Epigenome, Brain Laterality, ECT: New Review in brain sciences
Out on PubMed, from authors in Boston, is this article: Epigenome Defines Aberrant Brain Laterality in Major Mental Illnesses. Abdolmaleky HM, Nohesara S, Thiagalingam S. Brain Sci. 2024 Mar 7;14(3):261. doi: 10.3390/brainsci14030261. PMID: 38539649 The abstract is copied below: Brain-hemisphere asymmetry/laterality is a well-conserved biological feature of normal brain development. Several lines of evidence, confirmed by the meta-analysis of different studies, support the disruption of brain laterality in mental illnesses such as schizophrenia (SCZ), bipolar disorder (BD), attention-deficit/hyperactivity disorder (ADHD), obsessive compulsive disorder (OCD), and autism. Furthermore, as abnormal brain lateralization in the planum temporale (a critical structure in auditory language processing) has been reported in patients with SCZ, it has been considered a major cause for the onset of auditory verbal hallucinations. Interestingly, the peripheral counterparts of abnormal brain lat