Clinical Neuroscience of ECT (CNECT)

 Out on PubMed, from researchers in Sweden, is this study: Association between electroconvulsive therapy and time to readmission after a manic episode. Popiolek K , Arnison T, Bejerot S, Fall K, Landén M, Nordenskjöld A. Acta Psychiatr Scand. 2024 Apr 11. doi: 10.1111/acps.13689. Online ahead of print. PMID:  38604233 The abstract is copied below: Objective: The majority of patients hospitalized for treatment of a manic episode are readmitted within 2 years despite maintenance treatment. Electroconvulsive therapy (ECT) has been associated with lower rehospitalization rates in some psychiatric conditions, but its association with readmission after a manic episode has not been investigated. Therefore, the aim of this study was to determine whether the time to readmission in patients with mania treated with ECT was longer than in patients not treated with ECT and whether there were subgroups of patients that benefited more. Methods: This was a nationwide register-based, observational stud

Out on PubMed, from investigators in Denmark, is this study: Electroconvulsive Therapy and Risk of Road Traffic Accidents: A Danish Register-Based Cohort Study. Hjerrild S, Jørgensen MB, Dam OH, Tehrani E, Videbech P, Osler M. J ECT. 2022 Sep 6. doi: 10.1097/YCT.0000000000000881. Online ahead of print. PMID:  36095094 The abstract is copied below: Objective: The aim of the study is to examine whether electroconvulsive therapy (ECT) was associated with the subsequent risk of being involved in a road traffic accident. Methods: A cohort of all 375,435 patients older than 18 years with their first psychiatric hospital contact between 2003 and 2017 in the Danish National Patient Registry was followed for road traffic accidents until December 2018. Associations between ECT and road traffic accidents were examined using Cox regression analyses with multiple adjustments and using propensity score matching on sociodemographic and clinical variables. Results: A total of 8486 patients (0.2%) were

Out on PubMed, from researchers in Denmark, is this study: Mortality and acute somatic events following electroconvulsive therapy in patients with preexisting somatic comorbidity - a register-based nationwide Danish cohort study. Osler M, Rozing MP, Jorgensen MB, Jorgensen A. World J Biol Psychiatry. 2021 Oct 20:1-12. doi: 10.1080/15622975.2021.1995808. Online ahead of print. PMID:  34668447 The abstract is copied below: Objective:  To examine whether electroconvulsive therapy (ECT) is associated with risk of mortality and acute somatic events in patients with or without somatic comorbidity. Methods:  174,495 patients with an affective disorder, of whom 41% had somatic comorbidity, were followed from 2005 through 2018 for ECT, mortality, and acute somatic outcomes using Danish registers. The association of ECT with outcomes was estimated using Cox proportional hazard regression. Results:  Patients, of whom 6,943 (4.0%) had ECT, were followed for a median of 6.7 years. Compared to non-E

Out on PubMed, from the Nordenskjolds, is this study: Major adverse cardiovascular events following electroconvulsive therapy in depression: A register-based nationwide Swedish cohort study with 1-year follow-up. Nordenskjöld A, Güney P, Nordenskjöld AM. J Affect Disord. 2021 Oct 1:S0165-0327(21)01067-3. doi: 10.1016/j.jad.2021.09.108. Online ahead of print. PMID:  34606801 The abstract is copied below: Background:  The cardiovascular response during electroconvulsive therapy (ECT) could induce major adverse cardiovascular events (MACE) in the short-term, while reduced depression could decrease the risk of MACE in the long-term. The balance between these potential effects has not been thoroughly investigated. Methods:  This nationwide, registry-based cohort study included all patients admitted to Swedish hospitals due to moderate or severe unipolar depression between 2011 and 2018. Patients were divided into an ECT group and a non-ECT group, and followed for 1 year. Patients were match