Out on PubMed is this letter-to-the-editor from JECT:
The pdf is here.
These investigators, most of whom are from Duke, present a pilot study with 10 patients, testing augmentation of ECT with bupropion.
The idea is that concomitant use of an antidepressant might enhance/speed up antidepressant effect, and that, additionally, a putative pro-convulsant antidepressant might enhance seizure quality.
The results were inconclusive, but the authors suggest that a larger trial is warranted, and they are probably correct.
Rakesh G, Mischel NA, Gunderson-Falcone G, Anderson A, Copeland D, Szabo ST, Weiner RD.
J ECT. 2020 Mar 31. doi: 10.1097/YCT.0000000000000679. [Epub ahead of print] No abstract available.
- PMID:
- 32243338
The pdf is here.
These investigators, most of whom are from Duke, present a pilot study with 10 patients, testing augmentation of ECT with bupropion.
The idea is that concomitant use of an antidepressant might enhance/speed up antidepressant effect, and that, additionally, a putative pro-convulsant antidepressant might enhance seizure quality.
The results were inconclusive, but the authors suggest that a larger trial is warranted, and they are probably correct.
Comments
Post a Comment