E Field LTE in Molecular Psychiatry From Dr. Sartorius
Out on PubMed, from Alexander Sartorius, in Germany, is this LTE:
The pdf is here.
This is a very important and thoughtful letter; the technical details may be slightly beyond the full grasp of those of us with less background in physics, but the main points are clearly presented, so all can understand them. However, the greatest significance of this correspondence is challenging the published findings that many of us would feel inadequately prepared to question. A single lab, or one non-clinical investigator at the NIMH should not monopolize the literature discourse, particularly when clinical decisions in humans are suggested by the findings. I am reminded of the "bench-to-bedside" process, in which fast is usually applauded, but in which, sometimes, too fast, without adequate replication and testing, is problematic.
I recommend that all students/scholars of the mechanism of action of ECT literature read this letter.
Dr Kellner - thank you for sharing this sobering paper on the topic of e-field modeling in ECT. The topic requires a high level of knowledge in the area of electrical physics - a area where many like myself are deficient. It feels a bit like taking your automobile to the mechanic and not understanding most of what the mechanic is saying - we are forced to trust the speaker. This letter to the editor reminds us that , like taking your car to the mechanic, you sometime need a second opinion
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