ECT in Clozapine-Induced Myocarditis: New Case Report

Safety and Efficacy of Electroconvulsive Therapy in Clozapine-Induced Myocarditis.

Park N, Panzone J.J ECT. 2023 Mar 30. doi: 10.1097/YCT.0000000000000919. Online ahead of print.PMID: 36988550 
The report is here.
And here:
Here's a nicely presented case report, first-authored by a Cornell medical student. I recall treating a very similar patient  a few years ago.
The only only issue I would raise is the choice of electrode placement, in a patient in whom there are medical safety concerns; bilateral electrode placement might have been faster and more effective for the depressive symptoms in this patient.
Kudos to future Dr. Park.

Comments

Post a Comment

Popular posts from this blog

ECT plus Antidepressants: a Review

Out on PubMed, from researchers in Rotterdam, The Netherlands, is this review: Influence of an adjuvant antidepressant on the efficacy of  electroconvulsive  therapy: A systematic review and meta-analysis. Pluijms EM, Kamperman AM, Hoogendijk WJ, Birkenhäger TK, van den Broek WW. Aust N Z J Psychiatry. 2020 Sep 8:4867420952543. doi: 10.1177/0004867420952543. Online ahead of print. PMID:  32900217 Here is the "Conclusion" section from the text: Our results suggest that an adjuvant antidepressant enhances the efficacy of ECT in patients with major depression. Although the included studies had some methodological limitations, effect sizes were consistently small to moderate. We speculate that modern-day controlled trials using adequately dosed TCAs and MAOIs will most likely result in larger effect sizes. From a clinical point of view, we prefer an adjuvant TCA to an adjuvant MAOI, since TCAs are generally safe to use with ECT ( American Psychiatric Association, 2001 ; ...
Read more

Happy Birthday to Max Fink!

Image
Happy 102nd birthday to Max Fink, MD! Max Fink, an icon in our field, is one of the most influential ECT researchers, practitioners and advocates of all time. He has also been a friend and mentor to many of us in the ECT world, and we owe him a great debt of gratitude. Please join me in wishing him all the best today!                                                    Max Fink, October 2024, with Andrea and Charles Kellner
Read more

Clinical Phenotype of Behavioral-Variant Frontotemporal Dementia Reversed by ECT: A Case Report

Image
Out on PubMed, from authors in Germany, is this case report and literature review: Clinical Phenotype of Behavioral-Variant Frontotemporal Dementia Reversed by  ECT : A Case Report. Breitling B, Bartels C, Lange C, Bouter C, Falk HS, Wiltfang J, Zilles-Wegner D, Besse M. Neuropsychobiology. 2024 Dec 2:1-12. doi: 10.1159/000541668. Online ahead of print. PMID:  39622206 The abstract is copied below: Introduction: Diagnosis of frontotemporal dementia (FTD) remains difficult even in the presence of core clinical and imaging features. Furthermore, disease-modifying treatments are lacking. Case presentation: Here, we report a case of a patient with clinical and imaging features of FTD. Electroconvulsive therapy (ECT) was used to target affective and catatonic symptoms. After ECT, the patient showed improvements not only in affective symptoms but also in cognitive domains, leading to a marked improvement in the patient's level of functioning. Conclusion: Against the background of di...
Read more