C/M ECT: Small Study From Thailand

Effect of Continuation-Maintenance Electroconvulsive Therapy on Hospitalization: A Retrospective Mirror-Image Study.

Sombatcharoen-Non N, Yamnim T, Jullagate S, Ittasakul P.Neuropsychiatr Dis Treat. 2023 Jun 15;19:1427-1433. doi: 10.2147/NDT.S415878. eCollection 2023.PMID: 37342756 

The abstract is copied below:

Objective: To examine the effect of continuation-maintenance electroconvulsive therapy (ECT) on psychiatric hospitalization in Thai patients.

Methods: This retrospective mirror-image study reviewed medical records of Thai patients who received continuation-maintenance ECT at Ramathibodi Hospital, Bangkok, between September 2013 and December 2022. The initiation of continuation-maintenance ECT served as the index event, establishing pre-initiation and post-initiation periods. The primary outcome measured the differences in admissions and admission days before and after continuation-maintenance ECT.

Results: Forty-seven patients were included in the study, with diagnoses of schizophrenia (38.3%), schizoaffective disorder (21.3%), and bipolar disorder (19.1%) being the most common. The mean (standard deviation; SD) age was 44.6 (12.2) years. The total duration that patients received continuation-maintenance ECT was 53 ± 38.2 months. Following the initiation of ECT, there was a significant reduction in the median (interquartile range) number of hospitalizations for all patients (2 [2] versus 1 [2], p < 0.001), as well as for the psychotic disorder group (2 [2] versus 1 [2.75], p = 0.006) and the mood disorder group (2 [2] versus 1 [2], p = 0.02). Moreover, there was a significant reduction in the median (interquartile range) length of admission days for all patients after the initiation of continuation-maintenance ECT (66 [69] versus 20 [53], p < 0.001). Specifically, the psychotic disorder group (64.5 [74] versus 15.5 [62], p = 0.02) and mood disorder group (74 [57] versus 20 [54], p = 0.008) demonstrated statistically significant decreases in admission days.

Conclusion: Continuation-maintenance ECT may be an effective treatment option for reducing hospitalizations and admission days in patients with various psychiatric diagnoses. However, the study also highlights the need to carefully consider the potential adverse effects of ECT in clinical decision-making.

Keywords: Thai; continuation ECT; electroconvulsive therapy; hospitalization; maintenance ECT.

The article is here.
And from the text:



This is a modest-sized retrospective study, but it does add to the evidence base of the effectiveness of continuation/maintenance ECT.
The sentence about side effects in the abstract is somewhat discordant with the benign characterization in the discussion.
Kudos to our Thai colleagues for this contribution to the ECT literature.

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