NEJM Editorial About Ketamine Study

Out on Pubmed, about a couple of weeks ago, was this editorial:

Ketamine and ECT in Depression - Risks and Rewards.

Freedman R.N Engl J Med. 2023 May 24. doi: 10.1056/NEJMe2305130. Online ahead of print.PMID: 37224235 No abstract available.

The editorial is here:

As promised, here is the Freedman editorial that accompanied the Anand et al. ELEKT-D study.
I find it slightly misguided, much like the study, with a misunderstanding of the heterogeneity of the study population (chronic and comorbid does not equal severe) and a weird emphasis on the opioid qualities of ketamine.

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