Clinical Neuroscience of ECT (CNECT)

 Out on PubMed,from investigators mostly in Sweden, is this study: Blood biomarkers of neuronal injury and astrocytic reactivity in electroconvulsive therapy. Sigström R, Göteson A, Joas E, Pålsson E, Liberg B, Nordenskjöld A, Blennow K, Zetterberg H, Landén M. Mol Psychiatry. 2024 Oct 3. doi: 10.1038/s41380-024-02774-4. Online ahead of print. PMID:  39363047 The abstract is copied below: Despite electroconvulsive therapy (ECT) being recognized as an effective treatment for major depressive episodes (MDE), its application is subject to controversy due to concerns over cognitive side effects. The pathophysiology of these side effects is not well understood. Here, we examined the effects of ECT on blood-based biomarkers of neuronal injury and astrocytic reactivity. Participants with a major depressive episode (N = 99) underwent acute ECT. Blood was sampled just before (T0) and 30 min after (T1) the first ECT session, as well as just before the sixth session (T2; 48-72 h after the fifth s

 Out on PubMed, from authors in Korea, is this new guideline: Development of a Clinical Guideline for Suicide Prevention in Psychiatric Patients Based on the ADAPTE Methodology. Yang JH, Yoo J, Kang DH, Park CHK, Rhee SJ, Kim MJ, Lee SY, Shim SH, Moon JJ, Cho SJ, Kim SG, Kim MH, Lee J, Kang WS, Lee WY, Ahn YM. Psychiatry Investig. 2024 Sep 30. doi: 10.30773/pi.2024.0195. Online ahead of print. PMID:  39344367   The abstract is copied below: Objective:  Suicide is a significant public health issue, with South Korea having the highest suicide rate among Organisation for Economic Cooperation and Development countries. This study aimed to develop clinical guidelines for suicide prevention in psychiatric patients in Korea using the ADAPTE methodology. Methods:  The development process involved a comprehensive review of literature, expert consultations, and consensus-building using the Nominal Group Technique and Delphi method. The guidelines focus on evidence-based psychiatric treatments, i