Successful ECT for a 57-Year-Old Woman With Major Depressive Disorder and Dissociative Disorder: A Case Report and Literature Review in JECT

Out on PubMed, from authors in Japan, in JECT, is this case report: 

Successful Electroconvulsive Therapy for a 57-Year-Old Woman With Major Depressive Disorder and Dissociative Disorder: A Case Report and Literature Review.

Honda H, Nakamura T, Kubota N, Yokotsuka-Ishida S, Sasayama D, Washizuka S.J ECT. 2025 Apr 4. doi: 10.1097/YCT.0000000000001146. Online ahead of print.PMID: 40184540
The abstract is copied below:

Patients with dissociative disorders may have comorbid major depressive disorder (MDD), which is often difficult to treat. We report the case of a 57-year-old female patient with dissociative disorder comorbid with MDD who did not respond to multiple medications and psychotherapy and was treated with electroconvulsive therapy (ECT). The patient showed a reduction of greater than 50% in both Hamilton Depression Rating Scale and Dissociative Experiences Scale-II scores after ECT, indicating a significant improvement in both depressive and dissociative symptoms. Electroconvulsive therapy was effective not only for MDD but also potentially for dissociative symptoms. Thus, ECT may be considered a treatment option for patients with MDD and comorbid dissociative disorders.

Keywords: Dissociative Experiences Scale; dissociative disorder; electroconvulsive therapy; major depressive disorder.

The case report is here.
And from the text:
This is an interesting case report that reminds us of the complexity of clinical presentations. The patient's symptom recurrence suggests that taper of the acute ECT course and/or maintenance ECT would have been helpful.



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